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"AI won’t take your job. A person using AI will."

The real threat isn’t robots. It’s the people adapting faster than you.

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This week in the AI & tech world:

  • Isomorphic Labs’ AI-created drugs near human trials

  • xAI’s Grok 4 arrives

  • Perplexity drops AI browser

  • AI takes the wheel for managerial decisions

  • Moonvalley debuts filmmaker-friendly video AI

  • Tips, tricks & tutorials

  • Free resources & other cool updates

Reading time under 8 minutes

Latest updates

Isomorphic Labs’ AI-created drugs near human trials

Alphabet's AI-powered drug discovery company, Isomorphic Labs, is preparing to start its first human clinical trials for its AI-designed cancer drugs, with an ultimate goal of “solving all diseases.”

Here’s what you need to know:

  • The DeepMind spinoff has spent four years developing drugs using ‘AlphaFold 3’, an AI system for predicting protein structures and molecular interactions.

  • The team secured $600M in fresh funding in April, fueling both in-house drug candidates and major multi-billion dollar partnerships with Novartis and Eli Lilly.

  • The company envisions creating a "drug design engine" that could eventually generate treatments on demand to “solve all diseases.

  • Human trial is expected to begin soon, with oncology as the first clinical focus, and plans to license successful candidates after early trials.

Here’s what I think:

If Isomorphic’s approach delivers, pharma’s previous trial-and-error model could give way to a faster, more precise era where AI can design new treatments that get tested via simulations before entering the lab. “Solving all diseases” is a utopian vision — but at least one Nobel Prize winner agrees that it is in sight.

xAI’s Grok 4 arrives

xAI just announcedGrok 4 and Grok 4 Heavy’, its next-gen reasoning-only models that are “better than PHD levels in every subjectand deliver SOTA capabilities across benchmarks, including Arc-AGI and Humanity’s Last Exam.

Here’s what you need to know:

  • Grok 4 is a single-agent AI with voice, vision, and a 128K context window, while Grok 4 Heavy is its advanced sibling, with multiple agents to tackle complex tasks.

  • Both mark a major jump in benchmarks, achieving SOTA on Humanity's Last Exam, Arc-AGI-2, and AIME, and surpassing Gemini 2.5 Pro and OpenAI’s o3.

  • Grok 4 is available with the SuperGrok subscription at $30/month, while Grok 4 Heavy is part of the new SuperGrok Heavy plan priced at $300/month.

  • The new model is also available via API with a 256K-token context window and built-in search, priced at $3/million input tokens and $15/million output tokens.

Here’s what I think:

Despite being a relatively new player, Musk’s xAI is already challenging the AI heavyweights. The latest release showcases the power of its Colossus supercomputer and pushes the scaling frontier further.

Perplexity drops AI browser

Perplexity just announced the launch of ‘Comet, a new web browser with AI-powered search capabilities, aiming to reach users directly without going through Google Chrome, the most popular browser today.

Here’s what you need to know:

  • Comet comes with Perplexity’s AI search engine pre-installed and set as the default, offering users quick, AI-generated summaries of search results.

  • It also features Comet Assistant’, a built-in AI agent that aims to automate routine tasks like summarizing emails, managing tabs, and even interacting with webpages.

  • According to the company, Comet stores data locally and avoids using personal information for model training.

  • It is initially available to Perplexity’s $200/month Max plan subscribers and a select group of invitees, with broader access expected to roll out soon.

AI takes the wheel for managerial decisions

A new survey from Resume Builder found that more than 60% of managers are using AI tools to make critical business and personnel decisions, allowing the tech to determine raises, promotions, and firings with minimal oversight or training.

Here’s what you need to know:

  • Resume Builder surveyed 1,342 managers and found that 78% use AI to determine raises, 77% for promotions, and 64% for terminations.

  • ChatGPT dominated as the primary tool for 53% of AI-using managers, followed by Microsoft Copilot at 29% and Google Gemini at 16%.

  • One in five managers also frequently allow AI to make final decisions without human review, despite most never receiving formal AI training or guidelines.

  • Nearly half of the managers were asked to evaluate whether AI could replace their team members, with 43% following through on replacements.

Here’s what I think:

AI is already entrenched in the managerial department, but just as entry-level jobs have been the first to be automated, lower-level employees are again those being impacted by supervisors offloading decisions to ChatGPT. As models scale in intelligence, will owners automating managers out of the equation be next?

Moonvalley debuts filmmaker-friendly video AI

Moonvalley, a startup founded by ex-DeepMind researchers, just releasedMarey’ — a filmmaker-focused AI video model trained exclusively on licensed content that gives directors granular control over scenes.

Here’s what you need to know:

  • Marey is trained exclusively on licensed footage to avoid copyright issues that plague other AI startups, heavily sourced from indie filmmakers and agencies.

  • The model gives directors precise control over camera moves, character motion, backgrounds, and lighting, integrating directly into VFX workflows.

  • Pricing starts at $14.99 monthly for 100 credits, scaling up to $149.99 for 1,000 credits — with each five-second clip costing roughly $1-2 to render.

  • The company has raised over $100M to date and launched Marey alongside Asteria Film Co., an AI animation studio acquired by Moonvalley.

Here’s what I think:

As Hollywood’s AI anxiety peaks, Marey’ is a test of whether ethical AI can win over creators. With a “clean” training set and a platform that acts as a precise director tool instead of a “luck” based video slot machine, Marey could help shift AI’s narrative from existential threat to creative partnership.

Resources

Best ChatGPT FREE Course

Prompt of the week

Market research, competitive intelligence

Prompt: "You are a world-class industry analyst with expertise in market research, competitive intelligence, and strategic forecasting.

Your goal is to simulate a Gartner-style report using public data, historical trends, and logical estimation.

For each request:
• Generate clear, structured insights based on known market signals.
• Build data-backed forecasts using assumptions (state them).
• Identify top vendors and categorize them by niche, scale, or innovation.
• Highlight risks, emerging players, and future trends.

Be analytical, not vague. Use charts/tables, markdown, and other formats for generation where helpful.

Be explicit about what’s estimated vs known.

Use this structure:

1. Market Overview
2. Key Players
3. Forecast (1–3 years)
4. Opportunities & Risks
5. Strategic Insights"

AI Tips, Tricks & Tutorials

How to automate your job application with AI

Follow these steps:

  1. Open your preferred job site and log in to your account.

  2. Go to Runner H and sign up.

  3. Attach your resume, enter your prompt, and press Enter.

Sample Prompt: [CV attached] I have attached my CV. Go to [job site URL] and find [job title] in [location] and apply on my behalf.

  • In seconds, Runner H will start applying to your preferred jobs for you, automatically.

PRODUCTIVITY

Top AI tools of the week

  • 🎨 Soul Inpaint - Higgsfield AI’s new image editing tool for precise changes

  • 🗣️ Kyutai TTS - Open-source text-to-speech model for real-time use

  • 💎 Gems - Custom AI experts for Gemini, now available across Google Suite

  • 📄 Genspark AI Docs - Create a variety of document types with text prompts

  • 🎬 Marey - Filmmaker-focused AI video model trained on licensed content

AI IMAGES OF THE WEEK

Joker faces!

Prompt: "Jack Nicholson's Joker, Heath Ledger's Joker, Jared Leto's Joker, and Joaquin Phoenix's Joker are sitting at a bar drinking beers”.

Basket moon!

Prompt: "A photo taken from the side, basketball hoop with a full moon in the basketball hoop net, winner of the unsplash contest, conceptual art, highly detailed 4k photo, sunset lighting, net, playful composition, profile photo, photo taken in the evening, beautiful image, prize-winning color photo, winning photo, interesting angle”.

Top videos of the week

Popeyes AI-generated diss track ad!

The Immortal Blades Saga (AI-generated Sci-Fi series idea)

💡 The Latest in AI and Tech

  • A new ChatGPT tool called ‘Study Together (code named Tatertot) has started appearing on users’ platforms, hinting at a new collaborative workflow for students.

  • Google rolled out the ability to use first-frame image-to-video generations in Veo 3 with audio output, enhancing character consistency.

  • Genspark launchedAI Docs’, an agentic creator allowing users to generate and edit a variety of documents via natural language prompts.

  • Billionaire entrepreneur Mark Cuban said he believes the AI boom will lead to the world’s first trillionaire, and that it might just be “one dude in the basement”.

  • A new report suggests that Tech companies have eliminated more than 94,000 jobs this year and replaced them with AI systems.

  • Tencent’s Hunyuan releasedHunyuan 3D-PolyGen’, a new 3D AI model designed for professional art-grade outputs for game development and artist modeling.

  • Higgsfield AI introducedSoul ID’. Allows users to create fully personalized, consistent characters, with Soul-style high-aesthetic, fashion-grade realism.

  • OpenAI is set to launch its own web browser in the coming weeks that will challenge Google Chrome, featuring a ChatGPT-like chat interface and agentic integrations.

  • A departing Meta AI scientist posted a long internal essay comparing the company's culture to "metastatic cancer,” according to The Information, describing the AI unit as plagued by fear, confusion, and a lack of direction.

  • Google launched new updates to ‘MedGemma’, releasing two models to its suite of open medical AI tools, including a 27B multimodal model for interpreting medical images and patient records and a MedSigLIP tool for image and text analysis.

  • Luma AI launchedDream Lab LA’, a studio space where creatives can learn and use the startup’s AI video tools to help push into more entertainment production workflows.

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Thank you for your support and for being an amazing subscriber!🙌

That’s a wrap, my fellow Sapiens. Until next week:

Stay informed, stay adaptable, and keep thriving!

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